OK, I'll suggest a different option.
There is a tendency to start with the obvious R3 vs B2 since you get a 2D block, but if you don't knock the guy over you still need several 1D blocks or a dodge into a tackle zone. Since I never expect better than a pushback I'll assume pushbacks throughout.
R2 blocks B2 (1D), pushes straight back, followup to put TZ on B3.
R4 blocks B4 (2D), pushes diagonally to E4, no followup.
IF B4 is down, R3 can blitz B5 (1D) using 1 GFI and no dodges,
or if B4 is standing, R3 can move to F5, then a normal dodge will allow the blitz without a GFI.
If not a turnover yet, R1 would only block B1 if there is a reroll left because a TZ there is more use than having him fall over and letting R1 move to the endzone for a pass.
During the above I would only use a reroll to avoid a turnover, but both down in the B5 blitz should not be rerolled.